CBD Isolate

CBD Isolate – Bulk and Wholesale

CBD Isolate is a 99%+ purity crystalline cannabidiol powder produced from USA-grown hemp through extraction, winterization, distillation, and crystallization processes. The fine white crystalline powder is odorless, flavorless, and typically tests at non-detect Delta-9 THC on COA — making it the most versatile cannabidiol input available across edible, tincture, vape, topical, beverage, cosmetic, and pet product manufacturing. Available in bulk and wholesale quantities from 100 grams through 100+ kilogram tiers with significantly reduced pricing at higher volume. Material is produced in cGMP-compliant facilities and third-party tested through ISO 17025-accredited laboratories with full Certificates of Analysis available for review prior to purchase.

Product Specifications

• Chemical Name: Cannabidiol
• Chemical Formula: C₂₁H₃₀O₂
• Molecular Weight: 314.46 g/mol
• CAS Number: 13956-29-1
• Appearance: White to off-white fine crystalline powder
• Typical Purity: ≥99% cannabidiol
• Delta-9 THC Content: Non-detect to ≤0.3% by dry weight (batch-dependent, see COA)
• Solubility: Insoluble in water; soluble in oils, ethanol, propylene glycol, and other lipid carriers
• Melting Point: 66–67°C (151–153°F)
• Source: USA-grown licensed hemp
• Available Sizes: 100g, 250g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg, 100kg+
• Storage: Cool, dry, light-protected (see Storage and Handling)
• Typical Shelf Life: 24 months in sealed original packaging
• Lead Time: 1–3 business days for in-stock inventory; longer for custom volumes

What Is CBD?

CBD, short for cannabidiol, is the most extensively studied non-THC phytocannabinoid identified in hemp. With molecular formula C₂₁H₃₀O₂ and a molecular weight of 314.46 g/mol, CBD shares the same chemical formula as several other cannabinoids (including CBC and Δ⁹-THC) but differs in molecular structure — resulting in distinct physical properties and cannabinoid receptor interaction profiles. CBD is the second most abundant cannabinoid in most hemp cultivars and is recognized in research literature as one of the four major cannabinoids alongside CBG, CBN, and CBC. CBD isolate represents the endpoint of CBD refinement: pure cannabidiol crystallized from concentrated extract, with all other cannabinoids, terpenes, flavonoids, fats, waxes, and plant compounds removed.

How CBD Isolate Is Produced

1. Source Material. Production begins with USA-grown licensed industrial hemp meeting Farm Bill compliance standards (≤0.3% Delta-9 THC by dry weight at harvest). CBD-rich hemp cultivars are selected to optimize yield through the refinement chain.

2. Extraction. Cannabinoids are extracted from dried hemp biomass using either supercritical CO₂ extraction or ethanol extraction methods. CO₂ extraction yields a cleaner profile suitable for downstream isolate production; ethanol extraction provides higher throughput at industrial scale. Both methods produce a crude oil concentrate containing CBD alongside other cannabinoids, terpenes, and plant compounds.

3. Winterization. The crude oil is dissolved in cold ethanol and filtered at sub-zero temperatures to remove fats, waxes, and lipids that would otherwise compromise downstream purification. The winterized extract is significantly cleaner and more amenable to distillation.

4. Distillation. The winterized extract undergoes short-path molecular distillation, separating cannabinoids from remaining impurities based on differing boiling points under high vacuum. This step concentrates the CBD fraction into a refined distillate suitable for the final crystallization stage.

5. Crystallization. The CBD distillate is dissolved in a controlled solvent system and induced to crystallize under specific temperature and concentration parameters. As CBD molecules precipitate out as pure crystals, residual cannabinoids and impurities remain dissolved in solution and are removed through filtration and washing.

6. Final Purification and Milling. The crystallized CBD is washed to remove residual solvent and trace impurities, then dried under vacuum and milled into the fine crystalline powder format that defines finished CBD isolate. The result is a 99%+ pure cannabidiol powder ready for direct integration into commercial finished product formulations.

Manufacturing Applications

Tinctures and Dropper Formulations. CBD isolate dissolves into MCT oil, hemp seed oil, olive oil, and other lipid carriers at typical concentrations of 10–100 mg/mL. Heating to 60–80°C accelerates dissolution. Common in 500 mg, 1000 mg, 1500 mg, and 3000 mg per 30 mL retail SKUs.

Soft Gels and Capsules. Encapsulated as oil-suspended formulations or dry-blended into capsule fills at precise mg-per-unit doses (typically 10 mg, 25 mg, 50 mg). The crystalline powder form supports tight dosing accuracy in automated capsule filling lines.

Edibles (Gummies, Chocolates, Beverages). Incorporated into gummies and chocolates through pre-dissolution in a lipid carrier or emulsification system. Beverage applications require water-soluble emulsion preparation (nanoemulsion or microemulsion) since CBD is hydrophobic. Typical dose: 10–25 mg per finished serving.

Topical Products (Balms, Salves, Creams, Lotions). Active ingredient concentrations typically range from 0.5% to 5% by weight in topical formulations. CBD isolate's neutral color and odor profile preserves the visual and aromatic character of the finished product, unlike full or broad spectrum CBD inputs that contribute color and hemp aroma.

Skincare and Cosmetics. Used in serums, masks, eye creams, and premium skincare at concentrations of 0.5–2%. The flavorless, odorless, and colorless properties of CBD isolate are particularly valuable in cosmetic formulations where ingredient sensory characteristics matter to product positioning.

Vape Cartridge Formulations. Blended with crystal-resistant CBD distillate or terpene formulations to create CBD vape products. Pure CBD isolate alone tends to crystallize in cart hardware over time, so it's typically combined with crystal-resistant carrier systems for vape applications.

Pet Products. CBD isolate is the preferred input for pet tinctures, treats, and topicals — the verifiable THC-free profile addresses the heightened sensitivity of companion animals to THC content.

Quality Standards and Third-Party Lab Testing

CBD Isolate is sourced from suppliers operating cGMP-compliant production facilities, with finished material independently tested through ISO 17025-accredited third-party laboratories. Every batch ships with a Certificate of Analysis verifying cannabidiol potency, full cannabinoid panel (confirming the absence of other cannabinoids in the isolate), Delta-9 THC compliance, and screening for pesticides, heavy metals, residual solvents, mycotoxins, and microbial contamination. Batch-specific COAs are available for buyer review prior to purchase.

Compliance and Regulatory Considerations

CBD Isolate is produced from USA-grown hemp meeting the 2018 Farm Bill definition (Cannabis sativa L. with ≤0.3% Delta-9 THC by dry weight at harvest) and is federally compliant for interstate distribution. As CBD is non-converting to THC under finished-product processing conditions, CBD isolate generally faces standard hemp regulatory treatment. Buyers are responsible for verifying state-level CBD product registration and labeling requirements applicable to their finished products in destination markets.

Storage and Handling

Store CBD Isolate in a cool, dry environment between 15–25°C (59–77°F), protected from direct light and moisture. Sealed original packaging preserves potency and prevents cannabinoid oxidation. Refrigeration is not required but extends shelf life beyond the typical 24-month sealed specification. Once opened, transfer unused material to airtight, light-protective containers to minimize air exposure. Avoid prolonged exposure to temperatures above 30°C (86°F) or direct sunlight, which accelerate cannabinoid degradation.

Bulk and Wholesale Volume Tiers

CBD Isolate is available in the following standard volume configurations: 100g, 250g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg, and 100kg+. Pricing scales significantly with volume, with substantial per-kilogram reductions on orders of 5kg and above. Standing-order arrangements are available for buyers with recurring monthly volume needs, providing locked-in pricing and inventory reservation. Contact our sales team for current per-kilogram pricing across volume tiers.

Wholesale Buyers and Procurement Profiles

CBD Isolate is sourced by the broadest range of buyers in our wholesale catalog: brand manufacturers building retail CBD product lines across tinctures, soft gels, gummies, and topicals; private label operations supplying multiple downstream brand accounts; formulators developing precision-dosed edibles and beverage products requiring water-soluble emulsion preparation; cosmetic and skincare brands incorporating CBD as a featured active ingredient where neutral sensory characteristics are essential; pet product manufacturers; vape cart producers blending isolate with crystal-resistant carriers; and distributors supplying retail and manufacturing accounts with verifiable THC-free CBD input.

Submit an order request through the contact form on this page or call (303) 339-0343 for current pricing, COA documentation, and available volume.