CBGA Isolate

CBGA Isolate is a 99%+ pure crystalline cannabigerolic acid (CBGA) powder, the biosynthetic precursor cannabinoid often called the 'mother cannabinoid' because all major cannabinoids in the cannabis plant biosynthetically derive from CBGA. In the living hemp plant, CBGA is the foundational cannabinoid that enzymatic pathways convert into THCA, CBDA, CBCA, and other acidic precursor cannabinoids, which then decarboxylate to the familiar major cannabinoids (THC, CBD, CBC). CBGA itself decarboxylates to CBG with heat, time, or light exposure. CBGA isolate captures this foundational cannabinoid in its acidic precursor form for finished products positioned around the biosynthetic-precursor or unheated/uncured cannabinoid narrative. Available online in 100g, 500g and 1kg sizes, with larger volumes by bulk quote and significantly reduced pricing at higher volume. Material is produced in cGMP-compliant facilities and third-party tested through ISO 17025-accredited laboratories.

Bulk and Wholesale Volume Tiers

CBGA Isolate is sold online in 100g, 500g and 1kg sizes; larger volumes up to 100kg+ are available by bulk quote. Premium pricing reflects the timed-harvest cultivation requirements and cold-process production infrastructure required for commercial CBGA isolate production, temperature-controlled extraction, low-temperature distillation, and refrigerated post-production handling all add cost compared to standard CBG isolate. Standing-order arrangements are available for buyers with recurring volume needs.

Compare every CBG ingredient we carry by form, typical potency and common use. Typical potencies are batch-dependent; the batch COA for your lot ships with every order.

CBGA, short for cannabigerolic acid, is the biosynthetic precursor cannabinoid in the cannabis plant, often called the 'mother cannabinoid' because the major cannabinoids in hemp (THCA, CBDA, CBCA, and through decarboxylation, THC, CBD, CBC) are biosynthetically derived from CBGA through enzymatic pathways in the living plant. With molecular formula C₂₂H₃₂O₄ and molecular weight 360.49 g/mol, CBGA is structurally distinct from CBG (C₂₁H₃₂O₂, MW 316.48) by a carboxylic acid group (-COOH). CBGA decarboxylates to CBG at approximately 110°C / 230°F by losing the carboxylic acid group as carbon dioxide. In the hemp plant's biosynthetic pathway, CBGA can be converted enzymatically into THCA via THCA synthase, into CBDA via CBDA synthase, or into CBCA via CBCA synthase. This means hemp varieties dominant in CBD or THC have efficiently converted most of their CBGA into the downstream cannabinoids; the relatively small portion of unconverted CBGA remains as residual content. Commercial CBGA isolate is typically produced from CBG-rich hemp chemotypes in which a weakened synthase leaves most cannabinoid content as CBGA. As an acidic precursor cannabinoid, CBGA shares the temperature-sensitivity and storage considerations of CBDA and THCA.

CBGA Isolate is sourced by manufacturers building biosynthetic-precursor product lines positioned around the 'mother cannabinoid' narrative, by formulators developing multi-acidic-cannabinoid SKUs combining CBGA with CBDA and THCA (the distinctive application), by tincture producers building raw-cannabinoid product programs, by topical and skincare manufacturers seeking acidic-cannabinoid differentiation, by cold-fill beverage producers, by pet product manufacturers building raw-cannabinoid pet programs, and by analytical laboratories sourcing CBGA isolate as reference material, particularly important for laboratories testing acidic cannabinoid content in finished products. Cannabis biology researchers also source CBGA for studies of cannabinoid biosynthesis pathways.

Submit an order request through the contact form on this page or call (303) 339-0343 for current pricing, COA documentation, and available volume.